ENZYMOLOGICAL STUDY OF MNNG-INDUCED GASTRIC CARCINOMA IN RATS
نویسندگان
چکیده
منابع مشابه
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OBJECTIVE In this study, anticancer effects of mirtazapine on rats were investigated in an adenocarcinoma model induced by N-methyl-N-nitro-N-nitrosoguanidine (MNNG) and compared with those of cisplatin. MATERIALS AND METHODS For this purpose, 10 mg/kg doses of mirtazapine were administered orally to one group of rats, while 1 mg/kg doses of cisplatin were administered intraperitoneally to an...
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Gastric cancer remains a major global problem. In 2008, 989,600 new stomach cancer cases and 738,000 deaths occurred, accounting for 8% of the total cases and 10% of total deaths, respectively (Jemal et al., 2011). Notwithstanding the global declining incidence of gastric cancer, mortality is continuously rising in Asian countries (Hu et al., 2004). Surgery is considered as the gold standard fo...
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ژورنال
عنوان ژورنال: The KITAKANTO Medical Journal
سال: 1992
ISSN: 0023-1908,1883-6135
DOI: 10.2974/kmj1951.42.597